1. Tourette's Syndrome, Tics
   

2. Studies & Case Studies
   

3. Controlled Studies
   

4. Dronabinol
   

5. •      Müller-Vahl KR, Schneider U, Koblenz A, Jobges M, Kolbe H, Daldrup T, Emrich HM. Treatment of Tourette's syndrome with Delta 9-tetrahydrocannabinol (THC): a randomized crossover trial. Pharmacopsychiatry  2002;35(2):57-61.
   

6. •      Müller-Vahl KR, Schneider U, Prevedel H, Theloe K, Kolbe H, Daldrup T, Emrich HM. Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial. Journal of Clinical Psychiatry. 2003;64(4):459-65. 
   

7.  
   

8. Uncontrolled Studies
   

9. Dronabinol
   

10. •     Müller-Vahl KR, Schneider U, Kolbe H, Emrich HM. Treatment of Tourette-Syndrome with delta-9-Tetrahydrocannabinol. American Journal of Psychiatry 1999;156:495.
    

11.  
    

12. Case Reports, Surveys
    

13. Dronabinol
    

14. •     Deutsch SI, Rosse RB, Connor JM, Burket JA, Murphy ME, Fox FJ. Current status of cannabis treatment of multiple sclerosis with an illustrative case presentation of a patient with MS, complex vocal tics, paroxysmal dystonia, and marijuana dependence treated with dronabinol. CNS Spectr 2008;13(5):393-403.
    

15. •     Müller-Vahl KR, Schneider U, Emrich HM. Combined treatment of Tourette syndrome with delta-9-THC and dopamine receptor agonists. J Cannabis Ther 2002;2(3-4):145-54.
    

16. Cannabis (smoked)
    

17. •     Müller-Vahl KR, Kolbe H, Schneider U, Emrich HM. Cannabinoids: Possible role in pathophysiology of Gilles de la Tourette-syndrome. Acta Psychiatrica Scandinavica 1998;97:1-5.
    

18. •      Sandyk R, Awerbuch G. Marijuana and Tourette's Syndrome. Journal of Clinical Psychopharmacology 1988;8:444-445.
    

19. •      Hemming M, Yellowlees PM. Effective treatment of Tourette's syndrome with marijuana. J Psychopharmacol 1993; 7: 389-91.
    

You will find scientific information on most of the studies at Database on Clinical Studies and Case Reports.

1. 
   

2. •Improvement of symptoms or positive evaluation by authors
   

3. •No relevant change of symptoms or negative evaluation by authors
   

4. •Deterioration of symptoms

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